Clay Public Lecture


Technology-driven Statistics

Terry Speed, UC Berkeley and WEHI in Melbourne, Australia

Tuesday, October 30, 2007, at 7:00 PM

Harvard University Sceince Center -- Hall B

Forty years ago, biologists collected data in their notebooks. If they needed help from a statistician in analyzing and interpreting it, they would pass over a piece of paper with numbers on it. The theory on which statistical analyses was built a couple of decades earlier seemed entirely adequate for the task. When computers became widely available, analyses became easier and a little different. with the term "computer intensive" entering the lexicon. Now, in contemporary biology and many other areas, new technologies generate data whose quantity and complexity stretches both our hardware and our theory. Genome sequencing, genechips, mass spectrometers and a host of other technologies are now pushing statistics very hard, especially its theory. Terry Speed will talk about this revolution in data availability, and the revolution we need in the way we theorize about it.

Terry Speed splits his time between the Department of Statistics at the University of California, Berkeley and the Walter & Eliza Hall Institute of Medical Research (WEHI) in Melbourne, Australia. Originally trained in mathematics and statistics, he has had a life-long interest in genetics. After teaching mathematics and statistics in universities in Australia and the United Kingdom, and a spell in Australia's Commonwealth Scientific and Industrial Research Organization, he went to Berkeley 20 years ago. Since that time, his research and teaching interests have concerned the application of statistics to genetics and molecular biology. Within that subfield, eventually to be named bioinformatics, his interests are broad, including biomolecular sequence analysis, the mapping of genes in experimental animals and humans, and functional genomics. He has been particularly involved in the low level analysis of microarray data. Ten years ago he took the WEHI job, and now spends half of his time there, half in Berkeley, and the remaining half in the air somewhere in between.

Clay Public Lectures

The aim of this lecture series is to increase the awareness and understanding of mathematics — in the public at large as well as in the business, scientific and university communities.


Past Lectures:

The Music of the Primes Marcus du Sautoy of Oxford University, MIT, Compton Laboratories, May 8, 2008

Technology-driven Statistics Terry Speed of UC Berkeley, and WEHI, Harvard University Science Center, October 30, 2007

Surfing with Wavelets Ingrid Daubechies of Princeton University, MIT, Stata Center, April 10, 2007

Beyond Computation Michael Sipser of MIT. Harvard University, October 3, 2006

Mathematics and Magic Tricks Persi Diaconis of Stanford University. MIT, April 25, 2006

Escher and the Droste effect Hendrik mathematical microscope.Lenstra of Leiden University. Harvard, October 25, 2005

Are there unsolved problems about numbers? Barry Mazur, Harvard University. May 3, 2005

Four thousand years of mathematics in images Bill Casselman, University of British Columbia. April 26, 2005

Is there such a thing as infinity? Timothy Gowers, Cambridge University. March 22, 2004.
Lecture notes